Gymnema Extract,Gymnemic acid

Latin Name: Gymnema sylvestre .L

Content Specifications: 25.0% 75.0% Gymnemic acid Test by HPLC

Molecular Formula: C43H66O14

Molecular Mass:806.445257 g/mol

CAS No: 122168-40-5

Test Method: HPLC

Appearance: Yellow-brown fine powder

Description of Gymnema Extract,Gymnemic acid

Gymnema sylvestre extract has been shown to reduce blood sugar levels when used for an extended period of time. Additionally, Gymnema sylvestre extract reduces the taste of sugar when it is placed in the mouth, thus some use it to fight sugar cravings. From extract of the leaves were isolated glycosides known as Gymnemic acids, which exhibit anti-sweet activity. This effect, however, is short-lived, lasting a mere fifteen minutes. Gymnema sylvestre extract is currently being used in an all natural medication for diabetes with other ingredients such as cinnamon, chromium, zinc, biotin, banaba, huckleberry and bitter melon. Extracts of Gymnema is not only claimed to curb sweet tooths but also for treatment of as varied problems as hyperglycemia, obesity, high cholesterol levels, anemia and digestion.

Gymnemic acids are glycosides isolated from the leaves of Gymnema sylvestre (Asclepiadaceae). Gymnemic acids like ziziphin and hodulcine are anti-sweet compounds, or sweetness inhibitors. After chewing the leaves, solutions sweetened with sucrose taste like water.

More than 20 homologues of gymnemic acid are found in the leaves.Gymnemic acid 1 has the highest anti-sweet properties. It suppresses the sweetness of most of the sweeteners including intense artificial sweeteners such as aspartame and natural sweeteners such as thaumatin, a sweet protein. The anti-sweet activity is reversible, but sweetness recovery on the tongue can take more than 10 minutes.

A member of the milkweed family, Gymnema sylvestre is native to the tropical regions of India. Nicknamed the "sugar destroyer" because the leaves effectively block sweet tastes in the mouth when chewed, the herb is often promoted as an appetite suppressant and weight-loss agent. This claim has no evidence to support it, however. In fact, the capsules sold for this purpose don't even alter the taste in a person's mouth--the leaves need to be chewed directly for this purpose .

Function of Gymnema Extract,Gymnemic acid

1.Gymnemic acid lowers blood glucose through raising insulin levels by interfering with Islets of Langerhans in the pancreas.

2.It lowers serum cholesterol level and triglycerides level.

3.It reduces absorption of glucose and oleic acid in the intestine and improves uptake of glucose into cells.

4.It prevents adrenaline from stimulating the liver to produce glucose and reduce blood sugar level.

5.It interferes the ability of taste buds to taste sweet and bitter flavors.

Application of Gymnema Extract,Gymnemic acid

1. As Food and beverage ingredients.

2. As Healthy Products ingredients.

3. As Nutrition Supplements ingredients.

4. As Pharmaceutical Industry & General Drugs ingredients.

5. As a health food and cosmetic ingredients.