Genistein

Specifications: 98.0% Genistein Test by HPLC

Molecular Formula: C15H10O5

Molecular Mass: 270.24

CAS No: 446-72-0

Part of used:Flower

Test Method:HPLC

Active ingredient:Genistein

Odor:Characteristic

Appearance:Light Yellow Powder

Description of Genistein

What is Herbal Genista Extract Genistein?

Genistein is a variety of isoflavone which is most active, the product Genistein of our company is derived from dry and mature fruit of bean plant sophora Japonica. It is a pure and single element. It is a compound of heterocycle polyphenol.

Genistein can combine with estrogen receptor and have weak estrogen effect. So it is also called phytoestrogen. It is antagonistic to estrogen. It has protective effect or hormone related diseases. It can improve and prevent climacteric syndrome and osteoporosis. It can serve as food supplement to be widely used in various healthy food for the middle-aged and old people.

Genistein binds to and inhibits protein-tyrosine kinase, thereby disrupting signal transduction and inducing cell differentiation. This agent also inhibits topoisomerase-II, leading to DNA fragmentation and apoptosis, and induces G2/M cell cycle arrest. Genistein exhibits antioxidant, antiangiogenic, and immunosuppressive activities.

Function of Genistein

1.Genistein is classified as a phytoestrogen which are plant-derived nonsteroidal  compounds  that possess  estrogen-like biological activity. Genistein has been found to have both weak estrogenic and weak anti-estrogenic effects.Genistein has weak estrogenic activity as measured in in vivo and in vitro assays. In vivo,its estrogenic activity is one-third that of glycitein and four times greater than that of daidzein.

2.Genistein has been found to have a number of antioxidant activities. It is a scavenger of reactive oxygen species and inhibits lipid peroxidation.It also inhibits superoxide anion generation by the enzyme xanthine oxidase. In addition, genistein, in animal experiments, has been found to increase the activities of the antioxidant enzymes superoxide dismutase, glutathione peroxidase, catalase and glutathione reductase.

Application of Genistein

1.Applied in the field of pharmaceutical, it can be made into suppositories, lotions, injection, tablets,capsules and so on;

2. Applied in the field of health care products, it can be used as beauty care products for

women and also it can prevent blood diseases and cancer.